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Density and mechanical properties (e.g., compressibility or bulk modulus) are important cellular biophysical markers. As a result, developing a method to separate cells directly based on these properties benefits various applications including biological research, diagnosis, prognosis, and medical therapy. As a potential solution, surface acoustic wave (SAW) based cell separation has demonstrated advantages in terms of biocompatibility and compact device size. However, most SAW-reliant cell separations are achieved using an entangled eff

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