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The aims of the present study were to describe atraumatic proximal radial nerve entrapment (PRNE) and potential strategies for management. We performed a comprehensive search of 4 electronic databases for studies pertaining to patients with atraumatic PRNE. Studies published between 1930 and 2020 were included. Clinical presentation, nerve conduction studies, electromyography, and treatment methods were reviewed. In order to outline management strategies, 2 illustrative cases of acute PRNE were presented. We analyzed 12 studies involvin