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Chronic swelling is an important element in the development of ARHI. Interleukin-1 (IL-1) plays an integral role in irritation and may be related to ARHI. The goal of this study would be to evaluate the associations of single nucleotide polymorphisms (SNPs) of IL-1 receptor genes with ARHI in an elderly populace in Taiwan. METHOD Participants ≥65 years old had been recruited for audiometric examinations and hereditary analyses. The bilateral pure-tone average (PTA) o