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tigations are required for the continuous evaluation of efficacy and safety of HA. T.A. is funded by a Clinical Doctoral Research Fellowship (CDRF) grant (reference ICA-CDRF-2015-01-068) from the National Institute for Health Research (NIHR). The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health. The authors declare no conflict of interest. T.A. is funded by a Clinical Doctoral Research Fellowship (CDRF) grant (referen
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