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25-30% higher than the physiological values in the case of compression and on average 60% higher in the case of flexion). The use of long-segment fixator design shows better results than short-segment fixation. Considering both biomechanical and clinical aspects, three-segment fixation seems to be a compromise solution as it saves the patient from more extensive stiffening of the spinal motion segments. To detect the expression levels of miR-498 in the hepatoma cells and to clarify the biological roles of miR-498 in hepatoma by investig