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01) and remained stable from 1month to 5years after surgery (p  0.05). Contrast sensitivity in the photopic and mesopic condition showed no significant changes during 5-year follow-up (p  0.05). The SMILE procedure is satisfactory in terms of optical quality for correcting moderate and high myopia in the long-term period. ChiCTR-ONRC-13003114. ChiCTR-ONRC-13003114.This review article addresses challenges in the management of UNESCO Biosphere Reserves (BRs) by analyzing the value of research published in journals, chapters, and books that a