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Secondary clinical outcomes were comparable. At T2, alpha diversity was comparable (p0.05) between groups, whereas beta-diversity analysis revealed significant differences between PS and REF groups (both p=0.001). Actinobacteria were higher (both p0.01), and Proteobacteria, Firmicutes and Bacteroidetes were lower in PS versus REF. Gammaproteobacteria, Clostridia and Negativicutes were lower in both PS versus REF. TFF in EP infants was similar between SS and TS probiotics. Both probiotics were effective in reducing dysbiosis (high