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This research proposes the idea of double encryption, which is the combination of chaos synchronization of non-identical multi-fractional-order neural networks with multi-time-delays (FONNSMD) and symmetric encryption. Symmetric encryption is well known to be outstanding in speed and accuracy but less effective. Therefore, to increase the strength of data protection effectively, we combine both methods where the secret keys are generated from the third part of the neural network systems (NNS) and used only once to encrypt and decrypt th