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Among patients with HFpEF without AF, overweight (HR = 0.51, 95% CI 0.27-0.95) and obesity (HR = 0.64, 95% CI 0.43-0.98) were associated with a lower risk of all-cause death. In those with AF, obesity (HR = 0.62, 95% CI 0.40-0.95) but not overweight (HR = 0.81, 95% CI 0.54-1.21) was associated with a decreased risk of all-cause death. Conclusions The "obesity paradox" assessed by BMI exists in patients with HFpEF regardless of comorbid AF. Clinical Trial Registration https//clinicaltrials.gov, identifier NCT00094302.The inverted pendulum
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