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The intra-day and inter-day precisions expressed as general standard deviations had been 1.5-8.1% and 1.1-8.0per cent, correspondingly. Fiber-to-fiber reproducibility had been below 7.3%. The CMPs-SPME-UPLC-MS/MS technique had been used to identify trace CPs in genuine water examples with relative recoveries from 91.8% to 108%.The enantiomeric dedication of chiral medications in the environment is of growing issue since their enantiomers frequently exhibit stereoselectivity in environmental occurr