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The intraperitoneal injection of NDEA (35 mg/kg) began at four weeks of age and was performed at weekly intervals thereafter. Even though the fatality rate was significant within the KO mice, AsA supplementation (1.5 mg/ml into the drinking water) greatly stretched their life-spans. Just two out of 54 KO mice survived to 28 days, and both included around an order of magnitude greater quantity of tumor nodules in comparison to WT mice or KO mice with AsA supplementation. Histological and biochemical e
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