https://www.selleckchem.com/pr....oducts/tak-243-mln24
Background Rolling-circle replication (RCR) is a novel technology that has not been applied to cell-free DNA (cfDNA) testing until recently. Given the cost and simplicity advantages of this technology compared to other platforms currently used in cfDNA analysis, an assessment of RCR in clinical laboratories was performed. Here, we present the first validation study from clinical laboratories utilizing RCR technology. Methods 831 samples from spontaneously pregnant women carrying a singleton fetus, and 25 synthetic samples, were a