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es in clinical trials of UC. These findings have implications for clinical trial design in UC.SARS-CoV-2 was first identified in Wuhan in December 2019 and since then it has progressed into a pandemic that evolves continuously.1 As of May 5, 2022, there have been more than 81 million cases and 994,187 deaths in the United States.2 Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract consisting of ulcerative colitis and Crohn's disease treated with immunosuppressive/immunomodulatory agents. Ove