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This paper presents an active compensation strategy for RMS wavefront error of perturbed off-axis telescopes in the framework of nodal aberration theory. First, the orthogonalized expression of the wave aberration function in the vector form for perturbed off-axis telescopes is derived by using RMS normalization. The orthogonalized aberration function is applied to analytically describe the RMS wavefront error in perturbed off-axis telescopes with circular apertures. Then, the system compensation model for perturbed off-axis telescopes is esta

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