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re specificity is desired (stronger association between GFR and CVD events), while LMR and FAS appear more sensitive by including a higher number of patients with GFR 60 mL/min/1.73 m . In asymptomatic T2D patients, MDRD and CKD-EPI may be preferable when more specificity is desired (stronger association between GFR and CVD events), while LMR and FAS appear more sensitive by including a higher number of patients with GFR less then 60 mL/min/1.73 m2. Achieving adequate resection margins in breast conserving surgery is challenging and