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Workers from companies with no trade unions were more often advised on home office ergonomics (21.2% wTU versus 28.1% nTU). The odds of all analyzed health problems (pain, sore eyes, and anxiety) were increased in workers who reported having trade unions. Companies with trade unions were less ready for the forced transition to teleworking. These results contradict the traditional understanding of trade unions as a promoting factor for a healthy and safe working environment. Companies with trade unions were less ready for the forced tran