What Causes Trucking Accidents? Trucks make up a small portion of the vehicles that travel on the roads but they can cause serious injuries or death. Accidents involving large vehicles may occur when drivers become distracted or fail to pay attention to their blind spots. Driver fatigue can also be a factor in trucking accidents. These drivers often work long hours, without breaks, to meet their quotas. Driver Error Trucking accidents are the result of driver error which is a grave issue. Driver error can be caused by a variety of reasons. It