https://www.selleckchem.com/pr....oducts/iacs-010759-i
Our simulations reveal the physical mechanisms of interactions of lipid bilayers with solid surfaces that are responsible for the experimentally observed nonmonotonic particle size dependence of the uniformity and stability of lipid coatings particles smaller than the hydration layer thickness ( less then 2-3 nm) or larger than ∼20 nm are partially or fully enfolded by a lipid bilayer, whereas particles of the intermediate size (5-20 nm) cause membrane perforation and pore formation. In contrast, hydrophobic nanoparticles
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