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SIGNIFICANCE Neonatal Tsc1GFAP CKO mice recapitulate very early developmental aspects of EEG abnormalities, focal seizures, and an increased propensity for spasms. This mouse model may be helpful for early mechanistic and therapeutic studies of epileptogenesis in TSC. © 2020 International League Against Epilepsy.OBJECTIVE Few histological research reports have right analyzed age-related changes inside the lips, although noninvasive investigations of these changes tend to be increasing. Therefore, this resea

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