https://www.selleckchem.com/pr....oducts/mg-101-alln.h
Insulin has many important biological functions. Insulin interacts with the insulin receptor (IR) to play its physiological role and execute its functions. Here, we isolated porcine hepatocytes from young and aged pigs, which endogenously express the IR, as a model to study the intracellular signalling properties and cellular behaviour of insulin with aging. Firstly, we analysed the intracellular signal transduction that is triggered by insulin in porcine hepatocytes that were isolated from young and aged pigs and found that insulin