https://www.selleckchem.com/pr....oducts/tj-m2010-5.ht
Modulation of pathological neural circuit activity in the brain with a minimum of complications is an area of intense interest. The goal of the study was to alter neurons' physiological states without apparent damage of cellular integrity using stereotactic radiosurgery (SRS). We treated a 7.5mm-diameter target on the visual cortex of Göttingen minipigs with doses of 40, 60, 80, and 100Gy. Six months post-irradiation, the pigs were implanted with a 9mm-wide, eight-shank multi-electrode probe, which spanned the radiation focus as well