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The histologic analysis on several tumor subregions confirmed model suitability results on these areas. Only 3 histogram metrics, all derived from the meta-maps, were found to be statistically significant in differentiating low from high-grade STSs with an AUC higher than 89 %. Embedding model selection in the design of the diffusion parametric maps yields to histogram metrics of high discriminatory power in grading STSs. Embedding model selection in the design of the diffusion parametric maps yields to histogram metrics of high discri

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