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BACKGROUND Neurofibromatosis type 1 (NF1) is a cancer syndrome associated with many different cancer types. There are limited studies examining melanoma risk in this population. OBJECTIVE To identify melanoma cases in NF1 patients and compare melanoma incidence rates relative to a general population sample. METHODS A retrospective single institution case review of 857 NF1 patients (seen from 7/1997 to 7/2017) was conducted. We calculated age- and calendar period-adjusted standardized incidence ratios (SIRs) for white patients 20 yea
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