https://www.selleckchem.com/pr....oducts/bms303141.htm
The risk factors by bi-spectral index were sex, operation time, and the American Society of Anaesthesiologists classification. Compared to ETT intubation of 2h, the risk of MDRPI increased by 7.16 times (95% CI 1.35-38.0 and 7.93 times (95% CI 1.45-43.27) for3 and≥3h' duration, respectively. The difficulty of device repositioning can increase the incidence of MDRPI, and prolonged surgery was a significant risk factor. Thus, appropriate planning and correct equipment utilization is needed during prone position spine surgeries
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