https://www.selleckchem.com/products/AZD0530.html
Ranolazine significantly decreased the velocity of systolic contraction (+dP/dt) and the velocity of diastolic relaxation (-dP/dt) and developed pressure in normal and diabetic rat hearts. However, this negative effect was greater in normal hearts compared to diabetics. Ranolazine (100 μM) decreased the ATP level only in normal hearts and the ATP/ADP ratio decreased significantly ( 0.05) in both groups. This reduction was more prominent in normal hearts. It is concluded that in the isolated rat heart preparation, ranolazine has no
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