https://www.selleckchem.com/pr....oducts/Irinotecan-cp
In slightly more aggressive conditions, we observed transient accumulation of a decamer-of-dimers and appearance of 90-dimer capsids. In conditions where there is measurable kinetic trapping, we found that a highly diverse early intermediates accumulated within a fraction of a second and propagated into long-lived kinetically trapped states (≧90-mer). In all cases, intermediates between 35 and 90 subunits did not accumulate. These results are consistent with the presence of low barrier paths that connect early and late interme
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