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MXenes have aroused widespread interest in the biomedical field owing to their remarkable photo-thermal conversion capabilities combined with large specific surface areas. MXenes quantum dots (MQDs) have been synthesized either by the physical or chemical methods based on MXenes as precursors, which possess smaller size, higher photoluminescence, coupled with low cytotoxicity and many beneficial properties of MXenes, thereby having potential biomedical applications. Given this, this review summarized the synthesis methods, optical, surfa