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The review highlights the gap in toxicity studies and potential focus areas to overcome the existing challenges. We previously reported on a pilot study to assess the incorporation of a novel wellness assessment device, the Preventiometer (iPEx5 GmbH, Greifswald, Germany), into an academic medical practice. The present follow-up study expands on those data and evaluates the acceptability of the assessment process in a larger sample population. The aim of this study was to evaluate participant satisfaction with the Preventiometer wellne