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We examined the effects of collagen peptides (CP) supplementation on exercise-induced gastrointestinal (GI) stress. In a randomized, crossover design, 20 volunteers (16 males [Formula see text]O , 53.4 ± 5.9ml·kg ) completed 3 trials a non-exercise rest trial, with no supplement (REST) and then an exercise trial with CP (10g·day ) or placebo control (CON) supplements, which were consumed for 7days prior to, and 45min before, a 70min run at 70-90% of [Formula see text]O . Outcome measures included urinary lactulose and rhamnose (L/R), int