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79% vs. 76.62%, = 0.079), and complication incidences, although the latter group had larger nodules (9.11 mL vs. 13.79 mL, = 0.003), more energy delivered (3.44 kcal vs. 6.04 kcal, 0.001), and longer operation times (51.37 min vs. 69.2 min, 0.001). In the animal experiment, the 20 mL of liquid diffused quickly (within 10 min) from the vicinity of the thyroid to the mediastinum and retropharyngeal space. It was observed in the kidneys at 10 min and disappeared from the neck and chest space by 24 h. Continuous

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