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In addition, the results of global sensitivity analysis showed that 70% of output variance was determined by main effects in the M5 model and 30% by interaction effects. In this regard, the most influential parameters were flow depth and shear velocity, while the average velocity was the least influential factor.Urban air pollution is a serious environmental problem in developing countries worldwide, and health is a pressing issue in the megacities in Latin America. Buenos Aires is a megacity with an estimated moderate Air Quality Index
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