https://www.selleckchem.com/pr....oducts/tegatrabetan.
To construct a HIV-1 gp120 transgenic mouse model (gp120 ) with 7 nicotinic acetylcholine receptor ( 7nAChR) gene knockout. The 7nAChR gene knockout mice ( 7R ) were crossed with HIV-1gp120 transgenic mice (gp120 ) to generate F1 generation mice. We selected the F1 mice with the genotype of 7R /gp120 to mate to obtain the F2 mice. The genotypes of the F3 mice were identified by PCR, and the protein expressions in the double transgenic animal model was analyzed by immunohistochemistry. BV2 cells were treated with gp120 protein and 7
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