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0 ms/mmHg, P less then 0.05), while SBRS increased significantly (Post A 0.8 ± 0.2 to 1.5 ± 0.2 units･beat-1･mmHg-1, P less then 0.05) with an upward shift of the operating point. There were no differences in these variables between Post A and B. A clinical dose of GTN increased MSNA rapidly through effects on both CBRS and SBRS. These effects should be kept in mind when nitrates are used to clinically treat chest pain and acute coronary syndromes and used as vasodilators in experimental settings. In light of recent evidence that the co
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