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This implies that Fbx45 could potentially be a novel F-box protein that is unique to specific filamentous fungi such as Aspergillus types. Paracoccidioidomycosis (PCM) is a life-threatening systemic mycosis commonly reported in the Gran Chaco ecosystem. The disease is caused by different types through the genus Paracoccidioides, that are all endemic to Southern and Central The united states. Here, we sequenced and analyzed 31 isolates of Paracoccidioides across South America,

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