https://www.selleckchem.com/pr....oducts/l-ascorbic-ac
Knockdown of could also rescue TGF-β-induced loss of E-cadherin, and decreased TGF-β-induced vimentin and fibronectin expression; the elevation of MMP9 and MMP2 was also reversed by inhibition of . Further investigation confirmed the interaction of HMGA2 and , as overexpression of HMGA2 restores the effects of TGF-β on HT29 cells, which were attenuated by inhibition both in vitro and in vivo. Overall, our study revealed that interaction between and HMGA2 was involved in TGF-β-induced cell
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