https://ndi-091143inhibitor.co....m/itraq-quantitative
Lineage tracing of tubular epithelial cells (TECs) after AKI induction and long-lasting follow-up in mice showed time-dependent onset of clonal papillary tumors in an adenoma-carcinoma sequence. Among AKI-related paths, NOTCH1 overexpression in human pRCC related to even worse result and ended up being certain for type 2 pRCC. Mice overexpressing NOTCH1 in TECs developed papillary adenomas and type 2 pRCCs, and AKI accelerated this procedure. Lineage trac
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