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age ≥ 60 years; CKD Stage 3b-5; clinical stability (i.e. no hospitalization and ≤ 25% in creatinine upsurge in the last 3 months). Controls with normal renal purpose will undoubtedly be matched in terms of age, gender and diabetes mellitus (necessity calculated glomerular filtration rate ≥ 60 ml/min/1.73m for sale in the final 6 months). Exclusion requirements for situations and settings neuromuscular illness, life expectabetween fatigability and a
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