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Mice in which TonEBP had been particularly deleted in pancreatic hormonal progenitor cells exhibited faulty sugar homeostasis and a loss in islet size. Taken collectively, these results illustrate that TonEBP shields against ER stress-induced β-cell death by enhancing autophagy.Johne's illness (JD) is a life-threatening intestinal infection affecting ruminants, that causes important affordable losses globally. This ailment is brought on by Mycobacterium avium subsp.
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