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Nevertheless, the roles of IL-37 in pancreatic cancer tumors development and chemo-resistance continue to be unidentified. Methods Immunohistochemistry was used to investigate the correlation between IL-37 expression and clinicopathological popular features of pancreatic ductal adenocarcinoma (PDAC). Western-blot and RT-PCR had been made use of to confirm the correlation between IL-37 and hypoxia-inducible aspect (HIF)-1α. We performed chromatin immunoprecipi
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