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oned in patients with lymphopenia in recent complete blood count. We performed a multicenter study to assess the association between secondary antibody deficiency (immunoglobulin G [IgG] hypogammaglobulinemia combined with low levels of specific antibodies) and development of infection in kidney transplantation. We prospectively analyzed 250 adult kidney recipients at four centers. The assessment points were before transplantation and 7 and 30days after transplantation. The immune parameters were as follows IgG, IgA, and IgM and complem