https://www.selleckchem.com/pr....oducts/CP-690550.htm
Growing evidence suggests that dysfunctional astrocytes are crucial players in the development of mesial temporal lobe epilepsy (MTLE). Using a mouse model closely recapitulating key alterations of chronic human MTLE with hippocampal sclerosis, here we asked whether death of astrocytes contributes to the initiation of the disease and investigated potential underlying molecular mechanisms. Antibody staining was combined with confocal imaging and semiquantitative real-time polymerase chain reaction analysis to identify markers of differ