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In this work, a highly sensitive colorimetric paper-based optode for the determination of thiocyanate in urine samples was developed for the first time. The cocktail solution of the optode was composed of 5,10,15,20-tetrakis(4-octyloxyphenyl)porphyrin cobalt(II) complex (L), tridodecylmethylammonium chloride (TDMACl), 2-nitrophenyl octyl ether, and polyvinyl chloride as an ionophore, an ion exchanger, a plasticizer, and a polymer, respectively. The paper-based optode responded to thiocyanate by increasing the blue component in the RGB ind
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