https://www.selleckchem.com/pr....oducts/fezolinetant.
To evaluate the effect of possible changes in TM prestrain when the normal state of the ear is altered due to pathological modifications in the ME structure, we created a model with a perforation in the TM. It was shown that the change in vibration response after perforation is affected at low frequencies by a release of TM prestrain. In future studies, it may be necessary to incorporate prestrain in ME models to better understand the function of the diseased or reconstructed ME, which may be relevant for the development of reconst
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