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The mean Vancouver Scar Scale score at 3 months after surgery was 3.5 (range from 3 to 6) points. Four patients showed good flap survival at six-month follow-up. 3D printed prosthesis were all successfully implanted. The treatment of adult chronic osteomyelitis of lower extremities with lower abdominal implantable expander combined with flap technique can effectively increase the skin harvesting area, reduce the suture tension of abdominal skin harvesting area and the scar hyperplasia of abdominal skin harvesting area.This paper is the c