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To analyze the antibiotic prescription rate in low-risk patients evaluated at a telemedicine program that adopts antibiotic stewardship protocols. Adult patients who accessed a single direct-to-consumer telemedicine center (Jan/2019-Feb/202 were retrospectively enrolled. Diseases amenable to antimicrobial treatment were classified under five diagnostic groups upper respiratory tract infection (URI), acute pharyngotonsillitis (PT), acute sinusitis (AS), urinary tract infection (UTI), and acute diarrhea (AD). Physicians were trained on