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https://www.selleckchem.com/pr....oducts/isa-2011b.htm
Neurovascular coupling is typically considered as a master-slave relationship between the neurons and the cerebral vessels the neurons demand energy which the vessels supply in the form of glucose and oxygen. In the recent past, both theoretical and experimental studies have suggested that the neurovascular coupling is a bidirectional system, a loop that includes a feedback signal from the vessels influencing neural firing and plasticity. An integrated model of bidirectionally connected neural network and the vascular network is hence

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