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nt of treatment failure in children. © 2020 The Authors. Journal of the International AIDS Society published by John Wiley Sons Ltd on behalf of the International AIDS Society.BACKGROUND Aspirin is a classic anti-inflammatory drug and its anticancer effect has been previously explored in many types of cancer including colorectal cancer therapy. Programmed cell death-ligand 1 (PD-L1) is widely expressed in tumor cells and displays an inhibitory role in antitumor immunity. This study aimed to clarify the role of PD-L1 in aspirin-suppr