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Of 178 registered trials, 112 (62.92%) were in hospital settings, median planned recruitment was 100 participants (IQR 60, 168), and the majority (n=166, 93.26%) did not report results in their respective registries. Of 35 published trials, 31 (88.57%) were in hospital settings, median actual recruitment was 86 participants (IQR 55.5, 218), 10 (28.57%) did not reach recruitment targets, and 27 trials (77.14%) reported plans to share data. The findings of our study highlight limitations in the design and reporting practices of COVID-19 R

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