https://www.selleckchem.com/pr....oducts/lenalidomide-
Promising activities were confirmed in the resistant cyst form of the amoeba and in additional clinical Acanthamoeba strains, increasing their therapeutic potential. Mechanism-of-action studies revealed that these compounds produce apoptosis through reactive oxygen species (ROS)-mediated mitochondrial damage. These chemical families show promise for further optimization to produce effective antiacanthamoebal drugs.Shorter, more potent regimens are needed for tuberculosis. The nitroimidazole pretomanid was recently approved fo
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