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Of the 306 patients that received treatment, 193 received treatment longer than 12 months. In the multivariable logistic regression model, malnutrition at the time of treatment initiation was related with treatment intolerance (OR 2.559, 95% confidence interval [CI] 1.414-4.634, P = 0.002). Patients in the malnutrition group at the time of diagnosis exhibited lower survival (P less then 0.001) and malnutrition at the time of diagnosis was a significant risk for all-cause mortality (HR 2.755, 95% CI 1.610-4.475, P less then 0.001). Malnu